Anti-MAPT Polyclonal Antibody
Cat: K002115P
Summary:
| 【Product name】：Anti-MAPT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4137 | 【Swiss Prot】：P10636 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:100-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human MAPT | |
| 【Public Immunogen Range】：658-758aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse kidney using MAPT antibody at dilution of 1:100 (x40 lens).
Western blot analysis with MAPT antibody diluted at 1:1000;Lane: Mouse brain Rat spinal cord Rat brain.
Immunofluorescence analysis of A431 cells using MAPT antibody diluted at 1:100.