Anti-APEX1 Polyclonal Antibody - SAlexa Fluor 660
Cat: K002150P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-APEX1 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：328 | 【Swiss Prot】：P27695 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000.IF 1:50-100 | |
| 【Immunogen】：Recombinant protein of human APEX1 | |
| 【Public Immunogen Range】：1-318aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
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