Anti-GCG Polyclonal Antibody
Cat: K002159P
Summary:
| 【Product name】：Anti-GCG Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2641 | 【Swiss Prot】：P01275 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：IHC 1:100-200. IF 1:100-200 | |
| 【Immunogen】：Recombinant protein of human GCG | |
| 【Public Immunogen Range】：21-180aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Verified picture:
Immunohistochemistry of paraffin-embedded colon carcinoma(hu) using GCG antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of rat pancreas cells using GCG antibody diluted at 1:100.