Anti-SQSTM1 Polyclonal Antibody
Cat: K002179P
Summary:
| 【Product name】：Anti-SQSTM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8878 | 【Swiss Prot】：Q13501 |
| 【Tested applications】：IHC,WB,IF,IP | |
| 【Recommended dilution】：WB 1:500-2000. IP 0.5μg-4μg. IHC 1:20-50. IF 1:20-50. | |
| 【Immunogen】：Recombinant protein of human SQSTM1 | |
| 【Public Immunogen Range】：1-440aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Verified picture:
Western blot analysis with SQSTM1 antibody diluted at 1:1000;Lane: HeLa 293T.
Immunohistochemistry of paraffin-embedded human colon carcinoma with SQSTM1 antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using SQSTM1 antibody diluted at 1:100.