Anti-SQSTM1 Polyclonal Antibody
Cat: K002259P
Summary:
| 【Product name】：Anti-SQSTM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8878 | 【Swiss Prot】：Q13501 |
| 【Tested applications】：IF,IHC,WB,IP | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-100. IF 1:50-100. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human SQSTM1 | |
| 【Public Immunogen Range】：1-356aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Verified picture:
Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using SQSTM1 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with SQSTM1 antibody diluted at 1:1000;Lane: 293T HeLa.
Immunohistochemistry of paraffin-embedded Rat ovary with SQSTM1 antibody diluted at 1:75.
Immunofluorescence analysis of U2OS cells using SQSTM1 antibody diluted at 1:100.