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Anti-NCF2 Polyclonal Antibody - SAlexa Fluor 555
Cat: K002365P - SAlexa Fluor 555
Summary:
【Product name】:Anti-NCF2 Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4688 【Swiss Prot】:P19878
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human NCF2
【Public Immunogen Range】:227-526aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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