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Anti-CAT Polyclonal Antibody
Cat: K002366P
Summary:
【Product name】:Anti-CAT Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:847 【Swiss Prot】:P04040
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human CAT
【Public Immunogen Range】:1-225aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Liver cancer��hu�� using CAT antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with CAT antibody diluted at 1:2000;Lane: HeLa 293T HepG2 THP-1 Mouse liver Mouse kidney Rat liver Rat kidney.