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Anti-ARHGDIA Polyclonal Antibody
Cat: K002438P
Summary:
【Product name】:Anti-ARHGDIA Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:396 【Swiss Prot】:P52565
【Tested applications】:IF,WB
【Recommended dilution】:WB 1:500-1000.IF 1:50-200.
【Immunogen】:Recombinant protein of human ARHGDIA
【Public Immunogen Range】:1-204aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with ARHGDIA antibody diluted at 1:1000;Lane: 293T HeLa COS7 PC-12 Mouse lung Mouse spleen Mouse kidney.
Immunofluorescence analysis of Hela cells using RhoGDl antibody diluted at 1:100