Anti-SHMT2 Polyclonal Antibody
Cat: K002443P
Summary:
| 【Product name】：Anti-SHMT2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6472 | 【Swiss Prot】：P34897 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human SHMT2 | |
| 【Public Immunogen Range】：265-504aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded cervical cancer(hu) using SHMT2 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with SHMT2 antibody diluted at 1:1000;Lane: 293T SW620.