Anti-IL17A Polyclonal Antibody - SAlexa Fluor 405
Cat: K002562P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-IL17A Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3605 | 【Swiss Prot】：Q16552 |
| 【Tested applications】：IF,WB,IHC | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:50-200. IF 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human IL17A | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
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