Anti-EIF4EBP1 Polyclonal Antibody
Cat: K002576P
Summary:
| 【Product name】：Anti-EIF4EBP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1978 | 【Swiss Prot】：Q13541 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-200.IF 1:100-200 | |
| 【Immunogen】：A synthetic peptide of human EIF4EBP1 | |
| 【Public Immunogen Range】：50-118aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Verified picture:
Western blot analysis with EIF4EBP1 antibody diluted at 1:700;Lane: MCF7 HeLa Mouse skeletal muscle.