Anti-TOP1 Polyclonal Antibody
Cat: K002596P
Summary:
| 【Product name】：Anti-TOP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7150 | 【Swiss Prot】：P11387 |
| 【Tested applications】：IHC,WB,IP | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：A synthetic peptide of human TOP1 | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse liver using TOP1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with TOP1 antibody diluted at 1:1000;Lane: MCF7 SKOV3 SW480 Jurkat HeLa Mouse spleen Mouse ovary.