Anti-TYR Polyclonal Antibody - SAlexa Fluor 405
Cat: K002603P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-TYR Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7299 | 【Swiss Prot】：P14679 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human TYR | |
| 【Public Immunogen Range】：20-340aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
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