Anti-IL1A Polyclonal Antibody
Cat: K002751P
Summary:
| 【Product name】：Anti-IL1A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3552 | 【Swiss Prot】：P01583 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IL1A | |
| 【Public Immunogen Range】：113-267aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using IL1A antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with IL1A antibody diluted at 1:1000;Lane: Rat lung.
Immunohistochemistry of paraffin-embedded human colon carcinoma with IL1A antibody diluted at 1:75.