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Anti-PLAUR Polyclonal Antibody - SAlexa Fluor 750
Cat: K002772P - SAlexa Fluor 750
Summary:
【Product name】:Anti-PLAUR Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5329 【Swiss Prot】:Q03405
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human PLAUR
【Public Immunogen Range】:23-305aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
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