Anti-POT1 Polyclonal Antibody
Cat: K002805P
Summary:
| 【Product name】：Anti-POT1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：25913 | 【Swiss Prot】：Q9NUX5 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:200-2000 | |
| 【Immunogen】：Recombinant protein of human POT1 | |
| 【Public Immunogen Range】：497-634aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded rat kidney tissue using POT1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with POT1 antibody diluted at 1:1000;Lane: A431 HeLa DU145 Mouse liver.