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Anti-NQO1 Polyclonal Antibody
Cat: K002812P
Summary:
【Product name】:Anti-NQO1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1728 【Swiss Prot】:P15559
【Tested applications】:IF,WB,IHC
【Recommended dilution】:WB 1:500-1000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human NQO1
【Public Immunogen Range】:1-274aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Verified picture:
Western blot analysis with NQO1 antibody diluted at 1:1000;Lane: HepG2 MCF7 NIH3T3.
Immunofluorescence analysis of L929 cells using NQO1 antibody diluted at 1:100.