Anti-PRMT5 Polyclonal Antibody
Cat: K002814P
Summary:
| 【Product name】：Anti-PRMT5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10419 | 【Swiss Prot】：O14744 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PRMT5 | |
| 【Public Immunogen Range】：1-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using PRMT5 antibody at dilution of 1:100 (x100 lens,x200 lens).
Immunofluorescence analysis of U2OS cell using PRMT5 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with PRMT5 antibody diluted at 1:1000;Lane: Jurkat HepG2 HeLa NIH3T3 PC-12 COS-1.
Immunohistochemistry of paraffin-embedded human placenta with PRMT5 antibody diluted at 1:75.
Immunofluorescence analysis of H9C2 cells using PRMT5 antibody diluted at 1:100.