Anti-CASP7 Polyclonal Antibody
Cat: K002815P
Summary:
| 【Product name】：Anti-CASP7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：840 | 【Swiss Prot】：P55210 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CASP7 | |
| 【Public Immunogen Range】：150-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using Casp7 antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with CASP7 antibody diluted at 1:1000;Lane: Rat liver.
Immunohistochemistry of paraffin-embedded human colon with CASP7 antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using CASP7 antibody diluted at 1:100.