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Anti-CD4 Polyclonal Antibody
Cat: K002828P
Summary:
【Product name】:Anti-CD4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:920 【Swiss Prot】:P01730
【Tested applications】:IF,WB
【Recommended dilution】:WB 1:500-1000.IF 1:50-200
【Immunogen】:A synthetic peptide of human CD4
【Public Immunogen Range】:26-317aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Verified picture:
Western blot analysis with CD4 antibody diluted at 1:700;Lane: THP-1 Mouse thymus Mouse spleen.
Immunofluorescence analysis of Jurkat cells using CD4 antibody diluted at 1:100.