Anti-BTK Polyclonal Antibody
Cat: K002846P
Summary:
| 【Product name】：Anti-BTK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：695 | 【Swiss Prot】：Q06187 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-100 | |
| 【Immunogen】：Recombinant protein of human BTK | |
| 【Public Immunogen Range】：30-240aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse spleen using BTK antibody at dilution of 1:100 (x40 lens).