Anti-ITGAM Polyclonal Antibody - SAlexa Fluor 660
Cat: K002851P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-ITGAM Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3684 | 【Swiss Prot】：P11215 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ITGAM | |
| 【Public Immunogen Range】：145-340aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture: