Anti-BAD Polyclonal Antibody
Cat: K002861P
Summary:
| 【Product name】：Anti-BAD Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：572 | 【Swiss Prot】：Q92934 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human BAD | |
| 【Public Immunogen Range】：50-150aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Verified picture:
Immunohistochemistry of paraffin-embedded rat kidney using BAD antibody at dilution of 1:200 (x40 lens).
Immunofluorescence analysis of HeLa cell using BAD antibody. Blue: DAPI for nuclear staining.
Western blot analysis with BAD antibody diluted at 1:1000;Lane: HeLa Jurkat.