Anti-HDAC6 Polyclonal Antibody
Cat: K002952P
Summary:
| 【Product name】：Anti-HDAC6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10013 | 【Swiss Prot】：Q9UBN7 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HDAC6 | |
| 【Public Immunogen Range】：1-200aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using HDAC6 antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with HDAC6 antibody diluted at 1:1000;Lane: K-562 HeLa.
Immunohistochemistry of paraffin-embedded human stomach with HDAC6 antibody diluted at 1:100.