Anti-KPNA1 Polyclonal Antibody
Cat: K002957P
Summary:
| 【Product name】：Anti-KPNA1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3836 | 【Swiss Prot】：P52294 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human KPNA1 | |
| 【Public Immunogen Range】：1-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded human esophageal using KPNA1 antibody at dilution of 1:100 (400x lens).
Western blot analysis with KPNA1 antibody diluted at 1:1000;Lane: MCF7 K-562 HepG2 HeLa A549 Mouse brain Mouse heart.
Immunohistochemistry of paraffin-embedded human lung cancer with KPNA1 antibody diluted at 1:100.