Anti-FXN Polyclonal Antibody
Cat: K002959P
Summary:
| 【Product name】：Anti-FXN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2395 | 【Swiss Prot】：Q16595 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human FXN | |
| 【Public Immunogen Range】：42-210aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with FXN antibody diluted at 1:1000;Lane: 293T HepG2 K-562.
Immunohistochemistry of paraffin-embedded human liver cancer with FXN antibody diluted at 1:100.