Anti-CD3E Polyclonal Antibody
Cat: K002962P
Summary:
| 【Product name】：Anti-CD3E Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：916 | 【Swiss Prot】：P07766 |
| 【Tested applications】：FCM,WB,IP,IHC,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human CD3E | |
| 【Public Immunogen Range】：1-126aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Verified picture:
Western blot analysis with CD3E antibody diluted at 1:1000;Lane:Jurkat
Immunohistchemistry of paraffin-embedded Human tonsil with CD3E antibody diluted at 1:100