Anti-HMBS Polyclonal Antibody
Cat: K002977P
Summary:
| 【Product name】：Anti-HMBS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3145 | 【Swiss Prot】：P08397 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human HMBS | |
| 【Public Immunogen Range】：1-361aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded Skin cancer(hu) using HMBS antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with HMBS antibody diluted at 1:1000;Lane: HeLa Raji Mouse spleen.