Anti-TFF1 Polyclonal Antibody
Cat: K002985P
Summary:
| 【Product name】：Anti-TFF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7031 | 【Swiss Prot】：P04155 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TFF1 | |
| 【Public Immunogen Range】：25-84aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Verified picture:
Immunohistochemistry of paraffin-embedded human breast cancer using TFF1 antibody at dilution of 1:200 (x40 lens).
Western blot analysis with TFF1 antibody diluted at 1:700;Lane: MCF7 BT-474 MDA-MB-231 Rat stomach.
Immunohistochemistry of paraffin-embedded rat kidney with TFF1 antibody diluted at 1:100.