Anti-DCK Polyclonal Antibody
Cat: K002989P
Summary:
| 【Product name】：Anti-DCK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1633 | 【Swiss Prot】：P27707 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human DCK | |
| 【Public Immunogen Range】：1-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Verified picture:
Immunohistochemistry of paraffin-embedded rat kidney using DCK antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of MCF7 cell using DCK antibody. Blue: DAPI for nuclear staining.
Western blot analysis with DCK antibody diluted at 1:1000;Lane: Raji 293T Mouse liver Mouse brain Rat liver.
Immunohistochemistry of paraffin-embedded human gastric cancer with DCK antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using DCK antibody diluted at 1:100.