Anti-CYP24A1 Polyclonal Antibody
Cat: K002997P
Summary:
| 【Product name】：Anti-CYP24A1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1591 | 【Swiss Prot】：Q07973 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-100. | |
| 【Immunogen】：Recombinant protein of human CYP24A1 | |
| 【Public Immunogen Range】：36-448aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with CYP24A1 antibody diluted at 1:1000;Lane: Mouse kidney.
Immunohistochemistry of paraffin-embedded rat lung using CYP24A1 antibody at dilution of 1:200 (x40 lens).
Immunohistochemistry of paraffin-embedded rat pancreas with CYP24A1 antibody diluted at 1:75.