Anti-RPGR Polyclonal Antibody
Cat: K003029P
Summary:
| 【Product name】：Anti-RPGR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6103 | 【Swiss Prot】：Q92834 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human RPGR | |
| 【Public Immunogen Range】：1-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Verified picture:
Western blot analysis with RPGR antibody diluted at 1:1000;Lane: Rat testis.
Immunohistochemistry of paraffin-embedded mouse brain with RPGR antibody diluted at 1:100.
Immunofluorescence analysis of mouse retina cells using RPGR antibody diluted at 1:100.