Anti-FSCN1 Polyclonal Antibody
Cat: K003065P
Summary:
| 【Product name】：Anti-FSCN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6624 | 【Swiss Prot】：Q16658 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human FSCN1 | |
| 【Public Immunogen Range】：394-493aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Verified picture:
Western blot analysis with FSCN1 antibody diluted at 1:1000;Lane: U-251MG HeLa NCI-H460 HepG2 SH-SY5Y Mouse brain Mouse spinal cord.
Immunohistochemistry of paraffin-embedded rat stomach using FSCN1 antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded mouse testis with FSCN1 antibody diluted at 1:100.
Immunofluorescence analysis of C6 cells using FSCN1 antibody diluted at 1:100.