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Anti-FSCN1 Polyclonal Antibody - SAlexa Fluor 660
Cat: K003065P - SAlexa Fluor 660
Summary:
【Product name】:Anti-FSCN1 Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6624 【Swiss Prot】:Q16658
【Tested applications】:IF,IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human FSCN1
【Public Immunogen Range】:394-493aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
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