Anti-TNNC1 Polyclonal Antibody
Cat: K003078P
Summary:
| 【Product name】：Anti-TNNC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7134 | 【Swiss Prot】：P63316 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:1000-5000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TNNC1 | |
| 【Public Immunogen Range】：1-160aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Verified picture:
Western blot analysis with TNNC1 antibody diluted at 1:1000;Lane: Mouse heart Mouse lung Mouse skeletal muscle.
Immunofluorescence analysis of rat heart cells using TNNC1 antibody diluted at 1:100.