Anti-MMP8 Polyclonal Antibody
Cat: K003105P
Summary:
| 【Product name】：Anti-MMP8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4317 | 【Swiss Prot】：P22894 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human MMP8 | |
| 【Public Immunogen Range】：101-467aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with MMP8 antibody diluted at 1:1000;Lane: HepG2 A549 Jurkat.
Immunohistochemistry of paraffin-embedded human liver cancer with MMP8 antibody diluted at 1:100.