Anti-CHIT1 Polyclonal Antibody - SAlexa Fluor 350
Cat: K003148P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-CHIT1 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1118 | 【Swiss Prot】：Q13231 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CHIT1 | |
| 【Public Immunogen Range】：217-466aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
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