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Anti-EIF5A Polyclonal Antibody
Cat: K003149P
Summary:
【Product name】:Anti-EIF5A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1984 【Swiss Prot】:P63241
【Tested applications】:WB,IF,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human EIF5A
【Public Immunogen Range】:1-154aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Verified picture:
Immunohistochemistry of paraffin-embedded Liver cancer(hu) using EIF5A antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with EIF5A antibody diluted at 1:1000;Lane: HeLa 293T Raji 22Rv1 HepG2 K-562 U-251MG Mouse liver Mouse testis.
Immunohistochemistry of paraffin-embedded human breast cancer with EIF5A antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using EIF5A antibody diluted at 1:100.