Anti-PCK1 Polyclonal Antibody - Cy3.5
Cat: K003164P - Cy3.5
Summary:
| 【Product name】：Anti-PCK1 Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5105 | 【Swiss Prot】：P35558 |
| 【Tested applications】：IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human PCK1 | |
| 【Public Immunogen Range】：490-622aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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