Anti-RUNX1 Polyclonal Antibody
Cat: K003179P
Summary:
| 【Product name】：Anti-RUNX1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：861 | 【Swiss Prot】：Q01196 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:500-700. IHC 1:50-100. IF 1:50-100. | |
| 【Immunogen】：A synthetic peptide of human RUNX1 | |
| 【Public Immunogen Range】：171-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with RUNX1 antibody diluted at 1:1000;Lane: Jurkat Mouse lung Mouse spleen Mouse thymus Rat skeletal muscle.
Immunohistochemistry of paraffin-embedded rat brain using RUNX1 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded rat kidney with RUNX1 antibody diluted at 1:75.
Immunofluorescence analysis of A549 cells using RUNX1 antibody diluted at 1:100.