Anti-RUNX1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K003179P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-RUNX1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：861 | 【Swiss Prot】：Q01196 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human RUNX1 | |
| 【Public Immunogen Range】：171-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
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