Anti-TNFRSF11B Polyclonal Antibody
Cat: K003214P
Summary:
| 【Product name】：Anti-TNFRSF11B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4982 | 【Swiss Prot】：O00300 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TNFRSF11B | |
| 【Public Immunogen Range】：22-280aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Verified picture:
Immunohistochemistry of paraffin-embedded stomach cancer(hu) using TNFRSF11B antibody at dilution of 1:200.
Western blot analysis with TNFRSF11B antibody diluted at 1:1000;Lane: Mouse liver.
Immunohistochemistry of paraffin-embedded rat spleen with TNFRSF11B antibody diluted at 1:100.