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Anti-YWHAQ Polyclonal Antibody
Cat: K003421P
Summary:
【Product name】:Anti-YWHAQ Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10971 【Swiss Prot】:P27348
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:A synthetic peptide of human YWHAQ
【Public Immunogen Range】:49-149aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Verified picture:
Western blot analysis with YWHAQ antibody diluted at 1:1000;Lane: SW480 BT-474 HeLa Jurkat Mouse liver Mouse kidney Mouse brain.