Anti-KRT5 Polyclonal Antibody
Cat: K003458P
Summary:
| 【Product name】：Anti-KRT5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3852 | 【Swiss Prot】：P13647 |
| 【Tested applications】：IP,IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：A synthetic peptide of human KRT5 | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Verified picture:
Immunohistochemistry of paraffin-embedded skin cancer(hu) using KRT5 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with KRT5 antibody diluted at 1:1000;Lane: A375 PC-3.
Immunohistochemistry of paraffin-embedded Human esophageal cancer with KRT5 antibody diluted at 1:100.
Immunofluorescence analysis of L929 cells using KRT5 antibody diluted at 1:100.