Anti-DLK1 Polyclonal Antibody
Cat: K003466P
Summary:
| 【Product name】：Anti-DLK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8788 | 【Swiss Prot】：P80370 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-100.IF 1:50-100 | |
| 【Immunogen】：Recombinant protein of human DLK1 | |
| 【Public Immunogen Range】：24-303aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Verified picture:
Western blot analysis with DLK1 antibody diluted at 1:1000;Lane: K-562 HepG2 MCF7 SW620 Mouse liver Mouse kidney Mouse heart Rat liver.
Immunohistochemistry of paraffin-embedded rat pancreatic islet with DLK1 antibody diluted at 1:75.