Anti-EDNRB Polyclonal Antibody
Cat: K003529P
Summary:
| 【Product name】：Anti-EDNRB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1910 | 【Swiss Prot】：P24530 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human EDNRB | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using EDNRB antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with EDNRB antibody diluted at 1:1000;Lane: B cells Mouse lung Mouse brain.