Anti-PDK4 Polyclonal Antibody
Cat: K003577P
Summary:
| 【Product name】：Anti-PDK4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5166 | 【Swiss Prot】：Q16654 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human PDK4 | |
| 【Public Immunogen Range】：312-411aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Verified picture:
Immunohistochemistry of paraffin-embedded Ovarian cancer(hu) using PDK4 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with PDK4 antibody diluted at 1:1000;Lane: Mouse heart Rat heart.
Immunohistochemistry of paraffin-embedded rat heart with PDK4 antibody diluted at 1:100.