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Anti-UBE4A Polyclonal Antibody - SAlexa Fluor 405
Cat: K003658P - SAlexa Fluor 405
Summary:
【Product name】:Anti-UBE4A Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9354 【Swiss Prot】:Q14139
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-5000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human UBE4A
【Public Immunogen Range】:797-1066aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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