Anti-RNH1 Polyclonal Antibody
Cat: K003748P
Summary:
| 【Product name】：Anti-RNH1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6050 | 【Swiss Prot】：P13489 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:1000-2000.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RNH1 | |
| 【Public Immunogen Range】：202-461aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Verified picture:
Western blot analysis with RNH1 antibody diluted at 1:1500;Lane: Raji U-87MG HT-29 HeLa Mouse liver Mouse kidney Mouse lung Rat brain Rat lung.
Immunofluorescence analysis of C6 cells using RNH1 antibody diluted at 1:100.