Anti-COTL1 Polyclonal Antibody
Cat: K003820P
Summary:
| 【Product name】：Anti-COTL1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23406 | 【Swiss Prot】：Q14019 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human COTL1 | |
| 【Public Immunogen Range】：1-142aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain using COTL1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with COTL1 antibody diluted at 1:1000;Lane: Jurkat 293T U-251MG HeLa Mouse lung Mouse kidney Mouse spleen.
Immunohistochemistry of paraffin-embedded rat lung with COTL1 antibody diluted at 1:75.